Cells move in groups towards rigid tissues

A group of human mammary epithelial cells spreads asymmetrically over a growing rigid surface (right side of the image). The color lines show tracks of each cell (grey dots) every 10 hours.
A group of human mammary epithelial cells spreads asymmetrically over a growing rigid surface (right side of the image). The color lines show tracks of each cell (grey dots) every 10 hours.
Research
(09/09/2016)

A study published in the journal Science shows how different kinds of cells are attracted to tissue most rigid areas. The study challenges the traditional opinion, which said that cell movement is mainly guided by the variations in chemical concentration of proteins and ions. In this study it was been proved that when cells work between them, they are able to respond to variations in stiffness in a more efficient way than when isolated, an example of what it is called collective intelligence. The work is led by professors of the Department of Biomedicine and researchers from the Institute for Bioengineering of Catalonia (IBEC), Xavier Trepat and Pere Roca-Cusachs.

 

Link to the article

A group of human mammary epithelial cells spreads asymmetrically over a growing rigid surface (right side of the image). The color lines show tracks of each cell (grey dots) every 10 hours.
A group of human mammary epithelial cells spreads asymmetrically over a growing rigid surface (right side of the image). The color lines show tracks of each cell (grey dots) every 10 hours.
Research
09/09/2016

A study published in the journal Science shows how different kinds of cells are attracted to tissue most rigid areas. The study challenges the traditional opinion, which said that cell movement is mainly guided by the variations in chemical concentration of proteins and ions. In this study it was been proved that when cells work between them, they are able to respond to variations in stiffness in a more efficient way than when isolated, an example of what it is called collective intelligence. The work is led by professors of the Department of Biomedicine and researchers from the Institute for Bioengineering of Catalonia (IBEC), Xavier Trepat and Pere Roca-Cusachs.

 

Link to the article

Referència de l'article: R. Sunyer, V. Conte, J. Escribano, A. Elosegui-Artola, A. Labernadie, L. Valon, D. Navajas, J. M. García-Aznar, J. J. Muñoz, P. Roca-Cusachs and X. Trepat. Collective cell durotaxi emerges from long-range intercellular force transmission. Science, setembre 2016. Doi:xxxxxx