Stem cell therapy: a new era in brain regeneration after a stroke?

12/11/2025
Daniel Tornero Prieto, Alba Ortega Gascó, Santiago Ramos Bartolomé | Faculty of Medicine and Health Sciences, and Biology, University of Barcelona

Daniel Tornero Prieto, Alba Ortega Gascó, Santiago Ramos Bartolomé

Faculty of Medicine and Health Sciences, and Biology, University of Barcelona

Every year, millions of people see their lives change in a matter of minutes. A blood vessel travelling to the brain becomes blocked, neurons begin to die, and time is running out. It is a stroke, one of the leading causes of disability in adults. It is estimated that one in six people will suffer one during their lifetime

 The human brain is by far the most complex organ in our body. Its cellular architecture and organization into neural networks enable such sophisticated functions as language, memory and abstract decision-making. But that very complexity comes at a cost: brain tissue has a very limited capacity for regeneration. Unlike skin or liver, neurons that die are rarely replaced. 

Rehabilitation helps restore some function, but in many cases, patients live with permanent motor and cognitive limitations. In addition, after a stroke, the risk of depression, dementia and other neurodegenerative diseases increases. However, this could soon change thanks to the development of stem cell-based therapies. 

This article was originally published in The Conversation